American College of Toxicology: Policy statement on the use of animals in toxicology.

The American College of Toxicology is committed to advancing the science of toxicology as a means of protecting the health and safety of both people and animals for the preservation of our environment. The College recognizes that the continued use of animals for research is a necessary and critical component in pursuit of this commitment. However, it is the position of the College that when animals are used, careful consideration should be given to selection of the appropriate animal model and study design to address the purpose of the study. In all cases, the College seeks to promote the best possible science and the humane treatment of animals used to advance our understanding of human risk and safety assessment. Animals should be maintained and utilized in a proper and humane manner and in full conformance with all governing regulations and guidelines. The College subscribes to the concept of the 3 R’s (refinement, reduction and replacement) and supports research to enhance that concept where scientifically valid. The College further encourages all members to uphold the American College of Toxicology Code of Ethics wherein it states that each member shall uphold all laws, regulations, safety and ethical standards that apply to the welfare of co-workers, experimental procedures in animals and the environment.